16. Infectious Diseases - DNB QUESTIONS

• Point of care diagnosis for infections Jun 21
• Role of probiotics in gastrointestinal disorders Jun 20
• Role of prebiotics and probiotics in pediatrics practice Jun 19
• Probiotics in neonates Jun 15
• Short notes on prebiotics probiotics symbiotics Dec13
• Define probiotics prebiotics symbiotics. Mention characteristics mechanism of action and used of probiotics in pediatrics conceal practice Dec12 3+2+2+3
• Define role and principles of antibiotic stewardship in inpatient and outpatient settings in pediatrics practice Jun 20
• Principles of traditional antibiotic therapy Dec17
• Approach to of exanthematous fever in 14 month old child Jun 18
• Differential diagnosis of fever with rash in children Dec 20
• Enumerate causes of pyrexia of unknown origin in 5 year old child. Discuss diagnostic approach to fever with rash Dec 11;4+6
• Febrile neutropenia Jun 20
• Febrile neutropenia definition and management Dec15
• List cause of thrombocytopenia in a febrile child. How would you manage child with fever platelet count 25,000 and absolute neutrophil count 450/cumm Dec12
• Mechanism of antibiotic resistance Jun 20
• Diagnosis and management of staphylococcal toxic shock syndrome DEC17: 5
• Pathogenesis of tricks shock syndrome. Diagnostic criteria for TSS. Differential diagnosis and management of TSS. JUN 15; 3+2+2+3
• Pneumococcal vaccine Dec17
• Management of chhood with acute rheumatic fever with carditis Jun 21
• PANDAS Jun 16
• Diphtheric myocarditis Dec19
• Complications of diphtheria Dec 18
• Management and complications of Pertussis in infants Jun 21
• Diagnosis and management of Pertussis Apr 16
• Complications of Pertussis Dec 15
• Etiology pathogenesis prevention of Pertussis in children.Write the differences in efficacy, duration of protection and adverse effects between whole cell and acellular pertussis vaccine. Jun 14; 6+4mrks
• Typhoid conjugate vaccine. Jun 20
• Typhoid vaccines Jun 19
• a) MDR TB - Diagnosis and management. b) Antitoxin Therapy in Diphtheria - Guidelines.
• Discuss salient features of management of children with tuberculosis as per National Tuberculosis Elimination Programme (NTEP).
• a) Management of transfusion dependent thalassemia. b) Diagnosis of tuberculous meningitis.
• a) Pathophysiology of hypovolemic shock. b) Principles of newer diagnostic tests in tuberculosis.
• a) Role of CB-NAAT (Cartridge based nucleic acid amplification test) in diagnosis of pediatric tuberculosis. b) Nitric oxide therapy for persistent pulmonary hypertension.
• a) Recent advances in diagnosis of tuberculosis. b) Management of DKA.
• a) Treatment of diagnosed cases of cerebral malaria. b) Investigations for confirming diagnosis in suspected tuberculous meningitis.
• a) Strategies to prevent mother to child transmission of HIV infection. b) Capsule based Nucleic Acid Amplification test (Gene Xpert) for tuberculosis.
• a) MDR and XDR tuberculosis: treatment strategies. b) AVNRT (AV Nodal Re-entrant Tachycardia).
• Clinical presentation, investigations and treatment of Multi Drug Resistant TB.
• Describe etiopathogenesis, diagnosis and management of different types of neurotuberculosis.
• Discuss the recent guidelines for diagnosis and management of childhood tuberculosis.
• Outline the pharmacologic basis of short course chemotherapy of TB. Discuss the rationale, efficacy and characteristic of intermittent regimes.
• Describe the flow chart for diagnosis of childhood tuberculosis under RNTCP. Write briefly on DOT PLUS program.
• Describe clinical manifestations, diagnosis and management of Neuro-tuberculosis.
• a) Diagnosis and management of staphylococcal toxic shock syndrome b) Diagnosis and treatment of leptospirosis.
• a) Definition and treatment of dengue haemorrhagic fever. b) Clinical presentation and diagnosis of Mycoplasma pneumoniae infection. c) Clinical features and treatment of Chikungunya fever.
• a) Hidden Hunger in children. b) Rickettsial infection - when to suspect.
• a) Diagnostic lab tests for dengue fever. b) Diagnosis and treatment of Scrub Typhus.
• a) Causes and investigations for persistent pneumonia. b) Diagnosis and treatment of bronchopulmonary aspergillosis.
• Enumerate opportunistic infections in HIV infected children. How will you treat and prevent pneumocystis jiroveci infection.
• Mechanism of action, therapeutic usage with dosages and adverse effects in children on: a) Infliximab. b) Gamma globulins. c) Pegylated interferons.
• a) Diagnosis and prevention of congenital rubella syndrome. b) Current therapy of Kala-azar
• a) Discuss differential diagnoses of acute flaccid paralysis in tabular format. b) Describe patterns of weakness in Guillain Barre Syndrome and its variants and subtypes.
• a) Diagnosis and management of pertussis. b) VAPP (Vaccine Associated Paralytic Poliomyelitis).
• a) (i) Definition of polio eradication. (ii) Polio eradication in India. (iii) Immunization issues following polio eradication. b) Near drowning.
• What is Inactivated Polio Vaccine (IPV)? What are the advantages & disadvantages of IPV over OPV? What is the schedule of IPV as recommended by IAP?
• Enlist the common opportunistic infections in HIV infected children. Describe the clinical features, diagnosis and management of herpes simplex infection in HIV infected children.
• a) Management of chicken pox in an adolescent. b) Management and complications of pertussis in infants.
• a) Management of childhood autism. b) Treatment and outcome of neonatal and congenital varicella.
• a) Congenital varicella. b) Complications of Pertussis. c) Roseola Infantum.
• a) Congenital varicella. b) Complications of Pertussis. c) Roseola Infantum.
• a) X linked agammaglobulinemia. b) H1N1-Clinical features and management.
• a) Aerosol therapy for respiratory disorders. b) Current guidelines for management of H1N1 infection.
• a) Virology and epidemiology of Swine-flu. b) How is the disease categorized according to Govt. of India guidelines? c) Mention which children need to be immunized and who need to be given medication for the disease.
• a) Paediatric Covid - Classification and management. b) Malaria Vaccines.
• a) Psychosocial effects of COVID-19 on children. b) Classification and treatment of Multisystem Inflammatory Syndrome in Children (MIS-C).
• a) Prevention of COVID-19 infection. b) Indications of IVIG therapy in pediatric practice.
• Prevalence, clinical manifestations and management of Covid-19 infections in children.
• a) Rota virus vaccines: dosage, schedule & side effects. b) Mechanisms of antibiotic resistance.
• a) Rota virus vaccine b) Conjugate vaccines c) HPV vaccine
• a) HPV vaccine current status. b) Patterns of genetic inheritance.
• a) Rota virus vaccine b) Conjugate vaccines c) HPV vaccine
• a) Definition and treatment of dengue haemorrhagic fever. b) Clinical presentation and diagnosis of Mycoplasma pneumoniae infection. c) Clinical features and treatment of Chikungunya fever.
• Epidemiology, clinical features, prognosis and prevention of Japanese encephalitis.
• a) Pathophysiology of Dengue fever. b) Chronic constipation - Pathology.
• a) Dengue vaccines. b) CRISPR gene editing technology for child health.
• a) Fluid management in a child with Dengue Shock Syndrome and its complications. b) Immunotherapy.
• a) Fluid therapy in dengue hemorrhagic fever. b) Anti-retroviral therapy in pediatric HIV/AIDS as per NACO guideline.
• a) Diagnostic lab tests for dengue fever. b) Diagnosis and treatment of Scrub Typhus.
• Define severe dengue. Describe the WHO guidelines for its management. Enumerate the complications of severe dengue.
• a) Definition and treatment of dengue haemorrhagic fever. b) Clinical presentation and diagnosis of Mycoplasma pneumoniae infection. c) Clinical features and treatment of Chikungunya fever.
• Define severe dengue and describe the WHO guidelines for its management. Enumerate the indications for transfusion in dengue.
• What are the fluid, metabolic and biochemical changes in a child with severe dengue? Discuss the underlying pathophysiology.
• Define dengue hemorrhagic fever and dengue shock syndrome. Mention etiopathogenesis and management of dengue shock syndrome.
• Describe the etiology, mode of transmission, clinical features and management of viral hemorrhagic fever in children.
• a) Dog bite in chidren - Guidelines in Management. b) Enzyme Replacement Therapy.
• a) Monoclonal antibodies in post exposure prophylaxis of Rabies. b) Recent advances in insulin therapy.
• a) Congenital cataract: causes and prevention. b) Post exposure prophylaxis for dog bite.
• a) Anti-Rabies Vaccine - Different schedules, advantages of each schedule. b) Newborn screening test in relation to Endocrinology.
• How do you classify dog bites? Discuss its management.
• Write briefly about different types of vaccine against rabies. Discuss various schedules of pre and post-exposure prophylaxis for rabies.
• Write briefly about different types of vaccine against rabies. Discuss various schedules of pre and post-exposure prophylaxis for rabies.
• Enlist the common opportunistic infections in HIV infected children. Describe the clinical features, diagnosis and management of herpes simplex infection in HIV infected children.
• a) Transfusion associated hepatitis - Diagnosis & management. b) Management of worm infestation in children.
• a) Role of Cryptosporidium in causation of childhood diarrhea. b) WHO reduced osmolarity ORS.
• a) Diagnosis and prevention of congenital rubella syndrome. b) Current therapy of Kala-azar
• a) Paediatric Covid - Classification and management. b) Malaria Vaccines.
• a) Complications of severe falciparam malaria. b) Prevention of overweight and obesity in adolescents.
• a) Enumerate the criteria of discharge of low birth weight baby from SCNU (Special Care Newborn Unit). b) Recent National Malaria Management Guidelines.
• a) Treatment of diagnosed cases of cerebral malaria. b) Investigations for confirming diagnosis in suspected tuberculous meningitis.
• Clinical features, diagnostic tests and management of severe malaria in children.
• a) Newer antimalarial drugs. b) Failure to thrive.
• List the WHO criteria to diagnose severe malaria. Discuss the management of a child with cerebral malaria.
• Briefly discuss the laboratory diagnostic modalities of malaria and outline management protocol of Plasmodium falciparum malaria as per National Vector Borne Disease Control Program guidelines.
• Write short notes on: a) Zinc supplementation - when and how? b) Laboratory diagnosis of malaria.
• a) First Referral Unit. b) Management of neurocysticercosis c) Enumerate causes of 'Failure to Thrive' and a schematic evaluation plan for the same.